The impact of drug resistance on treatment outcomes in children and adolescents is a growing concern particularly in sub saharan africa where the majority of children living with hiv reside32 in general treatment options for children are limited as it is more difficult to develop paediatric drugs than it is for adults33 second line . Varicella vaccine is recommended for all non immune adolescents aged 14 years and adults immunisation providers should make every effort to identify and immunise non pregnant seronegative women of child bearing age see clinical features adolescents 14 years of age and adults need to receive 2 doses of varicella vaccine to achieve adequate protection from varicella 23 the 2 doses . Source measles data provided were reported voluntarily to cdc from state health departments alternate text this figure provides the number of measles cases in the united states from 1962 through 2011 after the introduction of the 1 dose measles vaccination program the number of reported measles cases decreased during the late 1960s and early 1970s to approximately 22000 75000 cases per